A study of anti-fungal resistance strains of Candida albicans yeast which isolated from clinical specimens of women Suffering from vaginal infections in Baqubah city
Author(s): Yasser Muwafaq Mehdi*, Rabab Majead Abed and Hadi R. Rasheed Al-Taai
Abstract
Vaginal swabs were collected from 40 ladies suffering from vaginal infections, their ages ranged between 20-50 years, attending the consulting clinic at Al-Batool Teaching Hospital in Baqubah for the period from December /2020 to February /2021.for married women. The samples that gave a positive test result for Candida albican infection were 20 samples The remaining 20 were negative. Of the 20 positive cases, 17 were pregnant women, their ages ranged between 20-30 years, and the non-pregnant women were 3 cases infected with Candida albicans, and their ages ranged between 31-50 years. Therefore, the infection rate of Candida albicans for the sample group was 80%, of which 59.4% were infected with C. albicans. Positive samples taken from pregnant women and 40.6% of samples taken from non-pregnant women. By using the Kirby-Bauer standard disk diffusion method, it was possible to assess the sensitivity and resistance of five C. albicans isolates to various antifungals. C. albicans had the highest level of resistance to various antifungals. Its resistance to Metroconazol (MZ), Fluconazol (FLU), and Ketoconazol (KCT) was all above 90%, but Amphotericin B (AMB) and Caspfungin (CAS) resistance rates were significantly lower at 25% and 45%, respectively. Antibiotic susceptibility testing of C. albicans for this study revealed that 12/20 (or 60%) of the isolates were multidrug resistant (MDR).