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Attenuating the Effects of Novel COVID-19 (SARS-CoV-2) Infection Induced Cytokine Storm and the Implications | Abstract

Journal of Research in Medical and Dental Science
eISSN No. 2347-2367 pISSN No. 2347-2545

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Attenuating the Effects of Novel COVID-19 (SARS-CoV-2) Infection Induced Cytokine Storm and the Implications

Author(s): Yashi Verma and Abhishek Ingole*

Abstract

Background: Cytokine storm in COVID-19 is one of the leading causes of deaths among the severe to critical patients and needs to be addressed with utmost priority. Medical interventions need timely updating regarding treatment while dealing with severe inflammation

Summary: Cytokine storm is the hyper inflammatory response which is generated by the body when the external pathogenic invasion is detected. But over activation can leads to severe inflammation among vital organs such as lungs and can damage the tissues resulting into multiple organ failure from which survival chances of the patients goes down. Rise in D dimer levels have found to be a common thread among the deceased patients which in turn can have the deleterious impact. Coronavirus disease 2019 or COVID-19 there is no method of curing exists that can be employed for every patient and which can have the ability to remedy the ailments since the newness of the pandemic. Therefore it becomes imperative to look for other methods instead of treatment methods and the other one is preventive measure.

Conclusion: Cytokine storm has established its fatal power and it is backed by the empirical evidences published across various studies. It is linked to the clinical manifestation of the COVID-19 in different types of patients. Various biomarkers can be used in order to detect the slipping of the patient’s condition into severe state. More study can shed some light on effective management of the cytokine storm which can in turn save more lives losing to cytokine storm induced medical complications in COVID-19 patients.

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