Case Report: Acquired von Willebrand Disease Causing Puberty Menorrhagia Secondary to Hypothyroidism
Author(s): Mangalpuri* and Yuvarani
Abstract
Eighteen-year-old patient presented with complaint of menorrhagia since menarche, along with severe anaemia. Investigations showed low vWF factor levels for her “B” Rh “+”ve- non-‘O’ blood group, without any family history of bleeding disorder or thyroid disfunction, further probing in thyroid function revealed severe hypothyroidism, though clinical examination did not show any signs suggestive of hypothyroidism. Oral Thyroxin for correction of hypothyroidism helped to stop menorrhagia effectively, showing consistency in diagnosis of Acquired von Willebrand Factor deficiency which in turn resulted in Factor VIII dysfunction secondary to hypothyroidism.