Challenges and future perspectives of gram negative multidrug resistant bacilli causing skin infections
Author(s): Muhammad Musthafa Poyil*
Abstract
Skin infections are considered as a group of various conditions that affecting the skin layers and soft tissues resulting superficial uncomplicated to complicated systemic infections which are caused by both gram positive as well as gram negative organisms. Mostly, the complicated skin infections were caused by gram negative bacilli such as Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae and Acinetobacter baumannii gained much attention owing to its multidrug resistance to existing antibiotics which further complicated the skin infection by prolonged hospitalization, cost for health care and mortality. In this review, we mainly focused the risk factor which predominantly complicates the skin infection, current treatment challenges as well as future direction for skin infection treatment and management.