CHONDROCALCINOSIS IN A HYPOTHYROID FEMALE, AN UNFORGOTTEN ENTITY-A CASE REPORT AND LITERATURE REVIEW
Author(s): Karthika Rajendran, Manjani S*, Balamurugan S and Khowsalya Subrajaa
Abstract
Arthropathy related to calcium pyrophosphate (CPP) dihydrate crystals has received little critical attention, until recently, CPPD disease was known as pseudogout. CPPD is commonly idiopathic, CPPD can also be associated with a number of metabolic diseases including, hypothyroidism, primary hyperparathyroidism, hereditary hemochromatosis, hypomagnesemia and hypophosphatasia. Chondrocalcinosis is more common in knees that have undergone meniscectomy than in contralateral non operated knees. Here we present a case of 70-year-old hypothyroid female presented with bilateral knee pain for 10 years. Patient was planned for right side knee replacement and incidentally per operative was found whitish chalky deposits which were sent for histopathological examination which revealed histomorphology features favoring calcium pyrophosphate crystalline disease (CPPD).