Clinical Presentation and Outcome of Acute PostStreptococcal Glomerulo Nephritis, in Sudanese Children
Author(s): Nahla Abdelrahman Allam, El Tigani M. Ali, Mohammed Hassan Alsonii, Yasser Mahjoop Bakiet
ntroduction: Acute Post-streptococcal glomerulonephritis (APSGN) is a common cause of acute glomerulonephritis, presented with hematuria, proteinurea, oliguria, hypertension and odem. The prognosis of children with APSGN is usually excellent. Methods: This is a retrospective and prospective cohort .study of Sudanese children with APSGN followed in tertiary care hospital between 2015 and 2021, patients who presented for follow up 1-5 years after initial diagnosis. Were assessed for protienurea, hematurea, urine for albumin creatnine ratio and Glomerular Filteration Rate (GFR). Results: Data of 144 children 99 males (68.7%) was analyzed. At presentation 102 (70.9%) had sever acute kidney disease requiring dialysis .On discharge 121(84.7%) recovered their renal function, 22 (15.2%) showed no recovery and one child died. Ninety out of 144 children presented to follow up 1-5 years after initial diagnosis .Fifty six of these children (62.2%) had normal blood pressure and GFR, while thirty four showed no recovery, twenty three (23) of them developed CKD, while 11 progressed to ESRD. Among children with normal GFR, 23 patients had micro albumiurea and hematurea. Conclusion: The establishment of the comprehensive diagnosis, treatment facility in our center since 2005 and educate pediatrician country wide has lead to better recognition and management of children presented with APSGN.