Comparison of Efficacy of Aceclofenac Sodium and Piroxicam in Patients Undergoing Surgical Removal of Impacted Third Molar- A Randomised Controlled Trial
Author(s): Yandeti Srinivasulu*, Abdul Wahab and Dinesh Prabu
Abstract
Aim: The aim of the study was assessing the efficacy of Piroxicam vs Aceclofenac sodium as an analgesic after removal of third molars when given post operatively. The study was a side-by-side comparison of two medications. Materials And Methods - A prospective randomized study conducted with 40 patients that required removal of mesio angularly impacted mandibular third molar. The systematic statistical analysis was performed after the data collection was done. Patients were categorized into two groups (Group 1 : piroxicam, Group 2 : Aceclofenac sodium) in a crossover manner .Subjective and objective observations recorded that include age, gender, and pain score using visual analog scale. Each patient was evaluated using a visual analogue scale. Results- Pain intensity at the postoperative 1st, 3rd, 5th, 7th day postoperative was less in Piroxicam group than Aceclofenac and there was significant difference seen statistically (p<0.001).Swelling and Trismus were not statistically significant, however there were significant reduction in Swelling and Trismus on 3nd day. Conclusion-Piroxicam had better efficacy and tolerability profile than Aceclofenac 100 mg in the management of pain after surgical removal of impacted mandibular third molar. Piroxicam is easy to use and the quick action of this formulation is advantages that are likely to improve patient compliance.