Correlation Duration of Oral Steroids Drug Administration by Intraocular Pressure in Patients with Systemic Lupus Erythematosus (SLE) in Dr. Mohammad Hoesin General Hospital Palembang
Author(s): Syarif Satya Graha, Fidalia1, Prima Mayasari, Nova Kurniati, Irsan Saleh
Abstract
Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease and multisystem organ involvement. SLE patients given treatment are manifold, one of which is with steroids. Long time drug administration depends on the clinical condition of the patient. Oral steroids may cause an increase in intraocular pressure, depending on the type of steroid that is administered, the route of administration and duration of taking the medication. To determine the correlation length of oral steroid drug administration by intraocular pressure in patients with SLE in dr. Mohammad Hoesin general hospital (RSMH) Palembang. This study was an observational study exploratory. Intra-ocular pressure examination uses Goldmann Tonometry Aplanation in patients with SLE who use oral steroid medication (methylprednisolone) in RSMH Palembang. Data were analyzed with correlation. Hypothesis test results correlation between duration of oral steroid drug (metylprednisolone) with intraocular pressure in patients with SLE using Spearman Correlations test obtained r = 0.054 and p = 0.637. There was no significant correlation between the duration of oral steroid medication (methylprednisolone) with intra-ocular pressure in patients with SLE. But looks very weak correlation strength.
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