Efficacy and Safety of COVID-19 Vaccine
Author(s): Aditi Medhekar, Ashok Mehendale and Komal Muneshwar*
Abstract
Background: COVID-19 is the emerging global medical emergency which has severely plagued the whole world. Large scale immunization program has already been started and it needs to be accelerated. Various types of vaccines such as messenger RNA vaccine, viral vector vaccine, protein subunit vaccines are being manufactured after emergency use authorization all across the world. These vaccine candidates need to be efficient and the reactogenicity must be as low as possible. The efficacy of the vaccine must be high and cohort of the studied patient should consist maximum number of subjects to get better results. As far now, all the vaccine candidates have shown good efficacy, but the mutation challenge is haunting as mutant variants can evade the vaccine protection. Preventive measures are one of the most effective measures available and which are time tested. Vaccines are one of the preventive measure and its various candidates have been granted emergency use authorization by the drug controlling agencies all round the world. More study needs to be done in order to solidify the efficacy results of the vaccine. The waning of the immunity post inoculation is one of the important needs to be studies as the worldwide debate on the booster dose has already been started.