Formulation and Evaluation of Ciprofloxacin Gel for Ophthalmic Drug Delivery
Author(s): Lalit Prakash*, Shivani, Manpreet Kaur, Kamlesh Sharma
Abstract
Ciprofloxacin hydrochloride belongs to the ?Žoroq‹noŽon‡ group which is crystalline pale yellow powder. ‹pro?Žošƒ…‹n hydrochloride acts as an antimicrobial agent for therapy of corneal ulcers due to bacterial strain. The main objective of present invention is to develop a framework for drug distribution to promote treatment adherence and dispensability is no exception. Thus, a topical drug transport system has been generated by using ointment formulation. In the present research a ciprofloxacin hydrochloride gel is developed using active pharmaceutical drugs, xanthan gum and HydroxyPropyl Methylcellulose (HPMC). Transparency, pH calculation, chelating ability, drug content, rheological analysis, and drug dissolution study were assessed for the prepared formulation.