Head and Neck Cancer Radiotherapy Effect on Some Properties | 54703

Journal of Research in Medical and Dental Science
eISSN No. 2347-2367 pISSN No. 2347-2545

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Head and Neck Cancer Radiotherapy Effect on Some Properties of Different Dental Restorative Materials: An in Vitro Study

Author(s): Sara said Eltohamy*, Mohamed M Kandil and Dina A El Refai


Aim: evaluation of the effect of HNC radiotherapy on diametral tensile strength, wear resistance, and color stability of Nanocomposite (Filtek Z-350XT), RMGI (Fuji II LC), Compomer (Composan glass).

Methods: A total of 300 specimens were prepared, 100 for each restorative material. 40 specimens from each material will not be exposed to radiation (control group). 30 specimens will be irradiated to 50 Gy and 30 specimens will be irradiated to 70 Gy. Diametral tensile strength (DTS), wear resistance, and color stability tests were measured for each group (n=10). One-way ANOVA was used to explore significance between groups followed by Tukey’s post hoc test. Independent t-test was carried to compare the color change of 50 Gy and 70 Gy groups.

Results: Reduction in DTS, and wear resistance was observed in the three materials after radiotherapy. Nano composite showed the highest DTS, and wear resistance, followed by compomer, while RMGI had the lowest values before and after radiation. Color change was observed also. RMGI had the least ΔE values, followed by nanocomposite, while compomer showed the highest ΔE values. These alterations in properties were radiation dose dependent.

Significance: The ionizing radiation doses used in HNC radiotherapy have a deteriorating effect on some properties of the three restorative materials used. Nanocomposite is the dental restorative material of choice in HNC patients undergoing radiotherapy due to its high mechanical properties and good color stability before and after radiation.

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