GET THE APP

Immunohistochemical Expression of Integrin in OSCC in Relation to Tumor Grade | Abstract

Journal of Research in Medical and Dental Science
eISSN No. 2347-2367 pISSN No. 2347-2545

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Immunohistochemical Expression of Integrin in OSCC in Relation to Tumor Grade

Author(s): Fatima Ghazi Al-Bayati*, Layla Sabri Yas

Abstract

Backgrounds: Squamous cell carcinoma (SCC) is identified as “a malignant epithelial neoplasm account 90% or more of oral lesion. Demonstrating squamous differentiation and have feature of keratin structure and intercellular bridges may be formed, so Integrin is a difficult of noncovalently complicated connected heterodimeric glycoproteins which is serve as adhesion particles of cell, co-operates with extracellular matrices (ECMs) like as laminin, fibronectin, vitronectin, and collagen, and have intercellular attachment function. Objective: This study is aimed to demonstrate the intra cytoplasmic integrin expression in the tumor cell of (OSCC) in relation to different malignancy grade. Materials and method: Seventeen case of formalin fixed -paraffin embedded (FFPE) tissue blocks that diagnosed as OSCC will be employed, all these cases were processed histologically and immunohistochemical to evaluate integrin expression. Results: the positive expression of integrin increase from WDSCC to PDSCC, and statistically there is highly significant appear (P <0.01) in relation of Expression of integrin to grade. Conclusion: Expression of integrin is increase with the histological grade of OSCC

Share this article

cappadocia tours
cappadocia hotels
cappadocia hotel
cappadocia balloon
cappadocia balloon flights

paper.io

agar io

wormax io