Incidence of Positive Endometrial Pipelle Biopsies for Endometrial Carcinoma Diagnosis in Patients with Abnormal Uterine Bleeding
Aim: The purpose of the study was to know the pervasiveness of positive endometrial biopsies in pre- and postmenopausal patients with abnormal uterine bleeding for the detection of endometrial cancer. Study design: A Cross-sectional study. Place and Duration: In the Obstetrics and Gynaecology Department of Sharif Postgraduate medical institute, Sharif medical city hospital Lahore Pakistan from May 2020 to May 2021. Methods: Pre- and postmenopausal women 35-70 years of age with abnormal uterine bleeding who met the inclusion and exclusion criteria were selected. A detailed interview and examination were obtained, informed consent, endometrial pipelle biopsy was performed. Each patient's biopsy was marked and sent to the Histopathology department for histopathological examination. A biopsy was considered positive if endometrial carcinoma was detected by histopathological examination and vice versa. Data were analyzed using SPSS version 20.0. For data analysis; Descriptive statistics were used. Results: Most of the patients (36.2%) belonged to the 35-45 age groups. The analysis of the distribution of births showed that the majority of women were multiparous (52.48%). Only 6.4% of cases were nulliparous. Most of the patients (58.2%) were postmenopausal. The most common symptom was menorrhagia, meaning that in 69.04% of cases; more than 80 ml of blood was lost per cycle in most cases. The most common histopathological finding in the Pipelle endometrium sample was the secretory endometrium, i.e. in 38.88% of cases. Conclusion: Pipelle biopsy is certainly a cost effective and beneficial method for identification of Endometrial carcinoma. By this, we can decrease the frequency of D&Cs performed in the operating room. The Pipelle accuracy is greater in postmenopausal women than in premenopausal females.