Investigating the Effect of Remote Limb Ischemic Preconditioning in Preventing Delirium in Patients Candidate for Coronary Artery Cardiopulmonary Bypass in Bushehr Heart Hospital
Background: Delirium is one of the common complications following open-heart surgery. Delirium is a fluctuating cognitive impairment and consciousness disorder and a common as well as acute problem for patients hospitalized in hospitals, complicating the course of patient improvement. Ischemic preconditioning can be a method to mitigate delirium of patients. The aim of the study is to investigate the effect of remote limb ischemic preconditioning in preventing delirium in patients undergoing coronary artery bypass graft surgery.
Methods: The present study is a randomized clinical control trial performed as interventional before and after intervention and control groups. The research population consisted of patients hospitalized in the ICU ward of Heart Center hospital of Bushehr city (Iran) to undergo CBAG or referred electively. In this plan, 80 patients participated chosen through convenient sampling, and then randomly assigned into intervention and control groups. The research instrument was demographics information form and Neecham scale to investigate the incidence of delirium. The data were analyzed by SPSS 22, whereby chi-do, Mann-Whitney, and Friedman nonparametric analysis of variance were used.
Findings: The mean delirium score before the intervention in the test group was 27.9 with standard deviation of 0.35, and in the control group it was 29.8 with standard deviation of 0.48 (p=0.399), which was the same in the two groups before the intervention and had no significant difference. The mean score of delirium after the intervention in the test group was 27.9 with standard deviation of 0.89 and in the control group it was 27.8 with a standard deviation of 0.96, suggesting insignificant difference between intervention and control groups.
Conclusion: The results of this research indicated that remote limb ischemic preconditioning cannot result in mitigation of delirium in CABG patients.