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Investigating the Interactive Effect of HMB-FA and Extrovert Physical Exercise on LDH Muscular Damage in Mature Male Rats | Abstract

Journal of Research in Medical and Dental Science
eISSN No. 2347-2367 pISSN No. 2347-2545

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Investigating the Interactive Effect of HMB-FA and Extrovert Physical Exercise on LDH Muscular Damage in Mature Male Rats

Author(s): Shahla Hojjat, Eidi Alikhani, Mohamad Reza Havasian and Niloufar Mahboubi

Abstract

Lactate is a glycolysis product that can be produced continuously by large cells at rest and even under sufficient oxygen conditions. It is suggested for extensive research to be conducted on the effects of HMB supplementation in human and animal samples. The aim of this study was to investigate the interactive effects of eccentric exercise and supplement HMB-FA on LDH in adult male rats. The 24 adult male rats split into four groups: control group (n=6), HMB (n=6), exercise (n=6) and Sport and HMB (n=6). After three familiarity session for experimental groups with training and obtain their 1RM, to supplement daily was administered weekly for two weeks. Then of course full load, eccentric resistance exercise was carried out. Upon completion of the exercise protocol blood of rats was carried out using LDH was measured by ELISA. Finally, data were analyzed using statistical software SPSS version 18. The finding no significant effect of supplementation with HMB-FA and eccentric resistance exercise on these variables have not found and the Conclusions this study found that in contrast to the results obtained in previous studies HMB-FA supplementation and eccentric resistance exercise no significant impact on the levels of LDH in adult male.

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