Investigating the Prevalence of Intestinal Parasitic Infections in Kidney Transplant Recipients
Author(s): Fariba Berenji, Hajar Imanfar, Fateme Nazemian, Veda Vakili, Abdolmajid Fata, Shadi Rahmani Khorasani1
Over the last two decades protozoa are one of the most common causes of infectious diseases in people with impaired immune system. Renal transplant recipients are one of the main groups with impaired immune system. The aim of this study has been to determine the prevalence of intestinal parasitic infections in renal transplant recipients of Mashhad. This descriptive study was conducted from January 23, 2015 to January 18, 2016 on renal transplant recipients of Mashhad. Three stool specimens were collected from each person after filling the questionnaire and informed consent. These samples were examined using four techniques, wet mount, formalinethyl Acetate concentration, Ziehl-Neelson staining and trichrome staining. Statistical package for social sciences (SPSS) 11.5 software (SPSS Inc., Chicago, Illinois, USA) was used for all statistical analyses. Standard descriptive statistics were applied to describe the pattern of the data. Chi-square test was used to examine the significance of the association between categorical data. In this study of the 71 patients renal transplant recipients, 41(57.7%) were male and 30(42.3%) were female. The maximum and minimum age of patients respectively was 69 and 14 years and the average age of persons was 39.5 years. In control group too, of the 71 subjects, 41(57.7%) were male and 30(42.3%) were female. The maximum and minimum age of them respectively was 70 and 15 years with the average age of 39.7 years. The results of this research showed that 45.07% of renal transplant recipients and 2.81% of control group were infected with intestinal parasites. The parasites detected among renal transplant recipients included 20(28.2%) Entromonas hominis, 11(15.5%) Giardia lamblia, 3(4.2%) Blastocystis hominis, 2(2.8%) Cyclospora cayetanensis. The intestinal parasitic infections in control group were 1(1.4%) Giardia lamblia and 1(1.4%) Blastocystis hominis. In statistical analysis results of prevalence intestinal parasitic infections, there was a significant difference between the renal transplant recipients and control group (P<0.001). This study indicated that intestinal parasitic infections have relatively high prevalence in renal transplant recipients of Mashhad. So these patients should be tested periodically to prevent morbidity and mortality from parasitic infections.