Myocardial Infarction with Non-Obstructive Coronary Arteries
Author(s): Fazal ur Rehman, Tarique Shahzad Chachar*, Iram Jehan Balouch, Imran Ellahi Soomro, Lalit Maheshwari and Riffat Sultana
Abstract
Background: Non-obstructive coronary artery disease affects certain people who are admitted to the hospital for an acute myocardial infarction (MINOCA). It is necessary to create risk categorization tools for these people since their prognosis is not always favorable. The purpose of this research was to examine the prognostic value of the GRACE score in a group of individuals with suspected MINOCA who were hospitalized. Methods: This study was conducted in Bolan Medical College Hospital Quetta Pakistan from 2june 2019 to July 2020. Total 56 patients with MINOCA were included. Patients' mortality and major adverse cardiac events (MACE) a combination of all-cause mortality and hospitalization from acute myocardial infarction (AMI), heart failure (HF), stroke (ischemic), & acute limb ischemia (ALI) were assessed for a period of one. The Grace score's discriminating power in predicting cardiovascular events was investigated using the Mann-Whitney U test and ROC curves. The level of significance was fixed at 5%. Results: In study of 56 MINOCA patients; 55.4 percent were female (median age 67). After a year, 5.5% of deaths occurred and 9.1% experienced MACE. It was shown that a higher GRACE score increased the probability of mortality (p=0.019; AUC 0.90; 95 percent CI 0.812-0.007) and MACE (p=0.034) Conclusion: The GRACE score is effective for risk classification of patients with MINOCA, since the criteria incorporate a variety of diagnoses and prognosis.
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