Obesity as a Threshold of Elevating Insulin and Leptin: A Population Based Cross Sectional Study
Obesity is a medical condition in which excess body fat has built up to the extent that it can have a negative impact on health and leads to a various diseases and conditions, including cardiovascular disease, type 2 diabetes, obstructive sleep apnea, some types of cancer, and osteoarthritis. This study aimed to evaluate the levels of insulin and leptin in non-obese and obese and its relationship. A total of 331 individuals, age 18 to 65 years (female 212 and male 119) were involved in the study which was conducted in the department of Physiology, Regional Institute of Medical Sciences, Imphal, Manipur, India. Collected blood samples were estimated insulin and leptin levels. All data were calculated the correlations between insulin and leptin. In this study, Insulin and leptin levels were significantly higher in obese compared to non-obese. Females showed significant increase among the groups of non-obese and obese. Data presents correlations between insulin and leptin as well as found relationships among leptin and obese. In this study, we conclude that with increasing insulin and leptin levels in obese, probability to prone prediabetic and other metabolic disorders are more.