Physiological Changes Related to the Metabolic Syndrome in Patients with Hypothyroidism | Abstract

Journal of Research in Medical and Dental Science
eISSN No. 2347-2367 pISSN No. 2347-2545

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Physiological Changes Related to the Metabolic Syndrome in Patients with Hypothyroidism

Author(s): Tariq Farhad, Sant Das, Kumar Lal, Maesh Kumar, Naresh Kumar, Kelash Jesrani and Niaz Hussain keerio*


Objectives: To study the physiological changes related with metabolic syndrome in patients of hypothyroidism and subclinical hypothyroidism. Study design: A Cross-sectional study. Place and duration: department of Family medicine, Ambulatory Health Servises SEHA Abu Dhabi United Arab Emirates from June 2020 to July 2021. Methodology: Serum levels of T3, T4 and TSH were assessed to diagnose hypothyroidism and subclinical hypothyroidism in patients. To evaluate the metabolic syndrome components, according to the guidelines of the International Diabetes Federation, body weight, waist circumference, blood pressure, fasting blood sugar estimate and lipid profile were tested. Results: Out of 180 patients 34.7% were having metabolic syndrome. The 21.66% patients of hypothyroidism suffered from raised blood glucose levels, 66.11% patients showed increased serum cholesterol levels, 59.54% patients had increased serum triglycerides levels, 17.77% had low or abnormal HDL levels, 40.55% patients had increased low density lipoproteins levels, 57.22% patients had raised systolic pressure, 62.77% had raised diastolic pressure and 70% patients were found to have increased waist circumference. The frequency of occurrence of waist circumference was highest in the study patients. The metabolic syndrome was more common in male as compared to female while there was no significant difference regarding the metabolic syndrome in different age groups. Conclusion: This study is therefore significant for developing approaches and techniques leading to better management and prevention of metabolic syndrome and hypothyroidism to decrease the cardiovascular risk factors and mortality.

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