Phyto-assisted Synthesis and Assessment of Anticancer Properties of Selenium Nanoparticles Prepared Using Banana Stem Extracts-An In-vitro Study
Author(s): Divij Khullar and S Rajeshkumar*
Abstract
Due to their inquisitive properties as compared to other selenium compounds, selenium nanoparticles have become a critical prospect in the field of medicine. They outperform selenite compounds in terms of anticancer, nontoxicity, and biocompatibility. The invasion of apoptotic pathways and cell cycle arrest, which eventually lead to blockage of other pathways, are the primary mechanisms behind SeNps' anticancer properties. Antibiotics, biomolecules, or phytochemical compounds found in bacteria or plants improve the anticancer properties of selenium nanoparticles by conjugation or surface alteration. Selenium, which is found in many enzymes including glutathione peroxidase (GPx), can improve chemotherapeutic activity by functioning as a functional division of the redox centre and protecting tissues from cellular damage caused by reactive oxygen species (ROS). SeNps have the potential to open up new regular methods for treating illnesses like cancer, and this article explains why.