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Preparation and Free Radical Scavenging Activity of Centella Asiatica Mediated Silver Nanoparticles | Abstract

Journal of Research in Medical and Dental Science
eISSN No. 2347-2367 pISSN No. 2347-2545

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Preparation and Free Radical Scavenging Activity of Centella Asiatica Mediated Silver Nanoparticles

Author(s): Obuli Ganesh Kishore S, Abirami Arthanari* and Rajeshkumar S

Abstract

Introduction: Centella asiatica commonly known as vallarai is a herbal plant. It is a plant with skin disease healing properties. Numerous preparations of this plant in various pharmaceutical forms recommended for several indications including neurological disorders are available all over the world. Free radical scavenging activity is the ability to delay ageing which can be simply termed as antioxidant property. Aim: The objective of this study is to assess the free radical scavenging activity of Centella asiatica mediated silver nanoparticles. Materials and methods: The plant extract was first prepared and the silver nanoparticles were added and mixed well. Silver nitrate was mixed with 50ml of water. 50ml vallarai extract was mixed with 50ml of the silver nanoparticle. This extract with properly synthesized nanoparticles was used to assess the antioxidant activity of Centella asiatica mediated silver nanoparticles. DPPH assay was performed to assess the free radical scavenging activity. Results: Centella asiatica along with silver nanoparticles has a positive outcome in the present study. It has also shown that it has a potent effect on antioxidant activity. The bioactive compounds may have significant health implications. These compounds may serve as antioxidants, enzyme inhibitors and inducers, receptor inhibitors and inducers, and gene expression inducers and inhibitors. Conclusion: Centella asiatica mediated silver nano particles was found to be a potent antioxidant.

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