Preventive Effect of Tamsulosin on Postoperative Urinary Retention in Benign per Anal Surgeries
Author(s): Yasaman Shariati, Mansooreh Vahedi, Shahin Fateh and Ali Cyrus
The aim of this study was to investigate preventive effect of Tamsulosin on postoperative urinary retention in benign perianal surgeries. This is a randomized, double-blind, placebo-controlled clinical trial. The population included 243 patients need surgery for benign perianal pathology. Patients randomized to the intervention group 1 (81 patients, 0.4 mg of tamsulosin under the administration of a single dose, six hours before the operation), the intervention group 2 (81 patients, 0.4 mg of tamsulosin under the administration of a dose of 6 hours before surgery, a single dose six hours after surgery) and control group (81 patients, under the administration of placebo) were enrolled. The incidence of urinary retention after surgery was recorded in the three groups. Data were analyzed by SPSS 20 software. 29 patients (11.93%) were suffering from urinary retention. Urinary retention was shown in groups 1, group 2 and placebo, in 8 (9.87%), 2 (2.46%) and 19 (23.45%) patients, respectively. (p<0.0001) urinary retention in Hemorrhoidectomy with 22 (17.47%) patients and in Sphincterotomy with 11 (16.41%) patients, significantly higher than the incidence of urinary retention were other injuries. The use of tamsulosin is effective in reduce the risk of urinary retention in patients with benign perianal surgery. Hemorrhoidectomy is the most associated with the incidence of urinary retention. Tamsulosin is a treatment with high performance to reduce the incidence of urinary retention.