Salivary Cortisol and Total Count of Subgingival Aerobic/Anaerobic Bacteria among Chronic Periodontitis Iraqi Armored Forces (Comparative Study)
Author(s): Omar Mizher Alazzawi* and Abbas Sabri Almizraqchi
Abstract
Background: Chronic periodontitis is a critical widespread health problem among population in both developing and industrialized countries with several etiological and associated risk factors. Many aerobic and anaerobic bacteria like aggregatibacter actinomycotemcomitans (a gram negative coccobacillus) and Porphyromonas Gingivalis act synergistically associated with this type of disease. Hypothalamicpituitary-adrenal axis release cortisol hormone which exerted in saliva ,and the drop of salivary melatonin hormone levels which act as antioxidant, anti-inflammatory and immunomodulatory agent, might tip the host–bacteria interaction in a favour of bacteria causing increase in off attachment loss .also stress caused by elevated cortisol hormone may affect how well people look after their oral hygiene and daily plaque removal which leads to development of periodontal disease especially chronic periodontitis .
Aim of the study: this study aims to determine the difference in the level of salivary cortisol,total count of aerobic and anaerobic bacteria and anxiety among chronic periodontitis group and periodontitis free group among Iraqi armored forces member and to evaluate the impact of salivary cortisol, total count aerobic and anaerobic bacteria and anxiety on the development of chronic periodontitis.
Material and methods: One hundred sixty subjects included in this study divided into two groups: Control group: Eighty subjects with healthy chronic periodontitis free, this group exposed to the basic periodontal examination.
Study group: Eighty subject with chronic periodontitis.
Salivary cortisol level measured and periodontal plaque serially diluted and cultured under aerobic and aerobic conditions for each group.
Anxiety estimated for each group by anxiety questionnaire (GAD-7).
Result: There was significant impact of salivary cortisol over the study, total count of bacteria, and anxiety.