Study of Vitamin D and Magnesium Levels in Newly Diagnosed Type 2 Diabetes Mellitus Patients in India
Author(s): Maitraye Basu*, Manasij Mitra and Gautam Sarker
Abstract
Introduction: The global burden of Diabetes Mellitus is huge. This research was undertaken with an aim to study the prevalence of Vitamin D deficiency and Magnesium deficiency and their relation with insulin resistance and insulin secretion defect in newly diagnosed Type 2 DM patients. Materials and methods: This was a hospital based cross-sectional comparative study on newly diagnosed Type 2 Diabetes Mellitus patients done over 18 months. Data was analysed using SPSS 21.0. Descriptive and Bivariate Analysis were used. P value less than 0.05 was considered significant. Results: 25-Hydroxy Vitamin D deficiency was found to be more prevalent in new onset Type 2 Diabetes Mellitus group. 19.17% cases had preclinical hypomagnesaemia. We found strong negative co-relationship between HOMA-IR and 25-HydroxyVitD and Mg Level of Cases (R2 0.4556 and R2 0.5413 respectively); between HbA1C and 25-HydroxyVitD and Mg Level of Cases (R2 0.5055 and R2 0.564 respectively); and between HOMA-B and 25-HydroxyVitD and Mg Level of Cases (R2 0.2337 and R2 0.2476 respectively). Conclusion: 25-Hydroxy Vitamin D levels and Magnesium were found to be significantly low in new onset Type 2 Diabetic Mellitus patients. We recommend screening for Vitamin D and Magnesium levels in newly diagnosed T2DM patients.