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Studying Effect of Fluoxetine on Improvement of Motor Performance in Patients with Ischemic Stroke | Abstract

Journal of Research in Medical and Dental Science
eISSN No. 2347-2367 pISSN No. 2347-2545

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Studying Effect of Fluoxetine on Improvement of Motor Performance in Patients with Ischemic Stroke

Author(s): Arash Mosarrezaii, Babak Ahmadi Salmasi, Seyed Abdolghafar Taghavi

Abstract

Ischemic strokes account for two-thirds of stroke cases, and the complications caused by it impose a lot of psychological and economic burden on both the individual and the society. This study evaluates the effect of onemonth treatment on NIHSS and BARTHEL INDEX criteria in these patients. This study is a clinical trial. Patients with stroke symptoms referred to Imam Khomeini Hospital in Urmia. After confirmation of ischemic stroke with CT scan or MRI, and having inclusion criteria, they were divided into case and control groups. Finally, the data were analyzed using SPSS software version 21. After one month the studies conducted showed that fluoxetine was effective on the overall score of NIHSS, facial paralysis score, upper limb movement score, and also on BARTHEL INDEX, but it had no positive effect on lower limb movement and dysarthria. Administration of fluoxetine in patients with ischemic stroke can increase motor performance in these patients.

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