Studying the Effect of Intravenous Injections of Ketorolac (IVIK) on Analgesia Control before and after using Tourniquet in Orthopedic Surgery of Femur and Tibia by General Anesthesia
Author(s): Hasan Zabetian, Farzad Sadeghi, Ali Falah, Navid Kalani
Postoperative pain is an unpleasant experience created due to different stimuli to which human reacts. This process leads to physiological disorders in all body systems. The purpose of this study was, thus, to evaluate the effect of IVIK on analgesia control before and after using tourniquet in orthopedic surgery of femur and tibia by general anesthesia. One hundred patients, candidate for femur and tibia surgeries aged 15-75, entered this double-blind clinical trial. Each patient was randomly assigned to one of the two groups of Ketorolac before and after tying the tourniquet. The visual criteria for pain during recovery were measured and completed at 6 and 12 hours after operation. Data were analyzed using descriptive (mean and percent) and inferential statistics (Man- Whitney). Mann-Whitney test showed no significant differences in pain scores in the two groups, before and after using tourniquet, in femur and tibia orthopedic surgery with general anesthesia (p-value>0.05). T-test showed a significant difference in heart rate between the two groups before and after tying the tourniquet at 30 minutes (p<0.05). No significant difference was found during the surgery between the two groups before and after tying the tourniquet regarding other vital signs (p> 0.05). The results showed no significant differences in the pain score in the groups before and after the use of tourniquet. Thus, as this used 30-mg of ketorolac was performed, it could not evaluate higher doses to reduce the need for analgesic in the two groups.