The Increasing Prevalence of DM in COVID-19 Patients: Is it | 89446

Journal of Research in Medical and Dental Science
eISSN No. 2347-2367 pISSN No. 2347-2545

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The Increasing Prevalence of DM in COVID-19 Patients: Is it a Matter of Diabetogenicity?

Author(s): Sufian Khalid, Khadeja Ismail Osman Farah, Awadalkareem AA, Musa Kheir D, Hisham M Abdelrahim, Motwakil lmam Awadelkareim, Ahmed ElSayed, Mohamed Osman Elamin*, Mohammed Salah, Ahmed A Osman, Ali M Alshehri, Hatim Abdullah Natto and Nazik Mubarak


Background: COVID-19 had made more than 197 million infections and 4 million deaths. Therefore, we need to assess the prevalence of DM among COVID-19 patients and its effect on the outcome. Objectives: We aim to assess the prevalence, risk factors and outcome of diabetes among COVID-19 patients. Methods: This was a prospective, cross-sectional, hospital-based study enrolled 400 COVID-19 patients and was conducted in COVID-19 isolation centers in North Sudan. Results: Males constituted 275 (68.9%) of the study participants, and the majority of participants were aged between 40 and 60 years 150(37.4%). The prevalence of DM was found to be 49.25% in the study participants. Diabetics were significantly more likely to have a respiratory rate higher than 30 (P=0.012), and oxygen saturation less than 93% (P<0.001), to develop shock (P=0.004), to require oxygen therapy (P<0.001), to be in tubated (P<0.001), to develop respiratory failure and organ failure (P<0.001), and to have a poorer outcome (P<0.001). New-onset diabetes occurred in 20 (5%) participants and their mortality was higher compared to non-patients with diabetes (P=0.04). The total mortality of participants was 15.8%. Factors associated with poorer outcome were older age (P<0.001), and having type I diabetes (P=0.025).Conclusion: The prevalence of diabetes is very high among COVID-19 patients, and is associated with a more severe disease and a poorer outcome. New onset diabetes was associated with poorer outcome compared to non-diabetics.

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