GET THE APP

To Study Clinical Profile and Short-Term Outcome of Pediatric Status Epilepticus at a Tertiary-Care Center in Central India

Journal of Research in Medical and Dental Science
eISSN No. 2347-2367 pISSN No. 2347-2545

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Research - (2022) Volume 10, Issue 6

To Study Clinical Profile and Short-Term Outcome of Pediatric Status Epilepticus at a Tertiary-Care Center in Central India

Paromita Roy and Saptarishi Bose*

*Correspondence: Saptarishi Bose, Department of Community Medicine, Great Eastern Medical School, Srikakulam, Andhra Pradesh, India, India,

Author info »

Abstract

Objective: To assess clinical profile and short term treatment outcomes of pediatric status epilepticus (SE) at a tertiary - care center in central India Methods: Prospective observational study. All Patients between age of 01month to 14 year presented as status epilepticus were managed as per IAP protocol of status epilepticus and, data was collected after taking written consent. They were studied for clinical presentation, efficacy of management and short-term outcome. Results: In our study on maximum age group children between 1-5 year i.e. 72 (68.57%). followed by >5-14 year were i.e. 21(20%) and <12month were 12(11.4%). Preponderance of male 55(52.4%) over female child 50(47.6 %) was observed. Most of 70.5% children present GTCS type of seizure on admission. Most of the cases CNS infections were predominant. In our study, presence of fever was documented in 85 subjects out of 105 cases. Our Study short term overall mortality rate was found to be 20(19) % child. Out of these 17(85 %) deaths belongs to the infectious etiology. Study was found that these 20 children mortality 17 (27.4%) mortality was these children where time taken to controlled seizure(>30 min).and those children start the management delay. in our study maximum number of subjects for termination of seizure lorazepam 65.7 %used as first line and in the remaining 36(34.3%) subjects midazolam was used In our study univariate analysis showed factors associated with a high risk of mortality in status epilepticus are prolonged duration of seizures (p- value, 0.015) time taken to control seizures (p-value <0.0001) nutritional status (p-value 0.008)We conclude that rapid termination of seizure important steps to good outcome in term of mortality and morbidity in SE. Conclusions: Acute symptomatic etiology, mainly acute CNS infections, is the leading cause of SE in this region. Early and pre-hospital management with benzodiazepines may improve SE outcome. Prolong duration of seizures and not respond to AED were major contributing factors in our study. All efforts to make to diagnose status epilepticus, so that we control seizure early by no delay for treatment.

Keywords

Bio-medical waste Management, Hospital waste, Nursing staff, Knowledge

Abstract

Background: According to BMW Rules 2016 Bio-Medical waste is any waste, which is generated during the diagnosis, treatment or immunization of human beings or animals or research activities pertaining thereto or in the production or testing of Biologicals. Hospitals are the major contributor of Bio-Medical Waste, and Hospital waste refers to all waste generated by hospitals, including infectious and non-infectious waste materials and hazardous waste. Materials and methods: A Hospital based Cross sectional Study was done in Great Eastern. Medical School & General Hospital, Srikakulam, during the period of October 2020 to November 2020.A convenient sample of 178 nursing staff in different cadre of 8 departments were selected randomly. A Predesigned & Pretested questionnaire was used and data regarding knowledge and practice was recorded. Results: A total of 178 study participants are interviewed and their responses were recorded. Most of them were Female (87%), 53.3% of them had MSc Nursing as qualification. Among the BSc Nursing staff 97.6% of them are aware of definition of hospital waste, 89.8% of staff nurses and 80% of A.N.M.s are aware of definition of hospital waste. Conclusion: The majority of nurses have good knowledge about infectious and non-infectious waste. The findings are in correlation with Saini et al. Majority of Nursing Staff had knowledge regarding storage time for infectious is less than 48 hrs. Good knowledge was seen in highly qualified nursing staff regarding disposal of hospital waste. BSc qualified nurses have better knowledge and practice about hospital waste than A.N.M. group

Author Info

Paromita Roy and Saptarishi Bose*

1Department of Dental, Great Eastern Medical School, Srikakulam, Andhra Pradesh, India, India
2Department of Community Medicine, Great Eastern Medical School, Srikakulam, Andhra Pradesh, India, India
 

Received: 06-Jun-2022, Manuscript No. JRMDS-22-65965; , Pre QC No. JRMDS-22-65965 (PQ); Editor assigned: 07-Jun-2022, Pre QC No. JRMDS-22-65965 (PQ); Reviewed: 21-Jun-2022, QC No. JRMDS-22-65965; Revised: 23-Jun-2022, Manuscript No. JRMDS-22-65965 (R); Published: 30-Jun-2022