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A Study on Nootropic Effect of Daucus Carota in Animal Models | Abstract

Journal of Research in Medical and Dental Science
eISSN No. 2347-2367 pISSN No. 2347-2545

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A Study on Nootropic Effect of Daucus Carota in Animal Models

Author(s): Sangamitrai, A Aswin Kumar and V Illamani*

Abstract

Daucus carota was studied for nootropic activity on wistar rats and albino mice. Diazepam induced amnesia using Elevated plus maze and Lithium induced head twitches were the two test, employed in rodents to predict nootropic potential of ethanolic extract of Daucus carota. In Diazepam induced amnesia test using elevated plus maze, the symbol of nootropic effect was reduced latency periods, i.e. reduced time taken for the rodent to reach the closed arm. In Lithium induced head twitches test, number of head twitches following administration of Daucus carota considerably reduced. In summary, ethanolic extract of Daucus carota showed significant nootropic activities possibly by subsequent inhibition of GABA-B receptors, which facilitate learning and memory process. Hence Daucus carota may be served as a potential natural resource for age related or other causes of memory loss.

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