Anticancer Effect of Cymodocea Serrulata Sea grass Crude Extract against Breast Cancer Cell Line
Author(s): Nandini Palanivel, P Sivaperumal*, D Ezhilarasan, Elumalai and Lakshmi T
Introduction: Breast cancer is cancerous cells which develop in breast cells. The cancer forms in either the lobules or the ducts of the breast. Cancer can also occur in the fatty tissue or the fibrous connective tissue within your breast. Cymodocea serrulata (Family Cymodoceaceae) Material and Methods: The sea grass Cymodocea serrulata was collected from Mimisal, Tamilnadu. The sea grass was washed thoroughly with tap water then shade dried on table tissue paper for 3 weeks and turned into a fine powder and then used for the research. Results: The crude extract obtained from Cymodocea serrulata shows potential anticancer activities. Analysis of cell morphology changes by a phase contrast microscope was done. 3 X 104 cells were seeded in 6 well plates and treated (concentration for MCF-7 cells) for 24h. At the end of the incubation period, the medium was removed and cells were washed once with a phosphate buffer saline (PBS pH 7.4). The plates were observed under a phase contrast microscope. Conclusion: The anticancer effect of Cymodocea serrulata crude extract against breast cancer cell line is found. Therefore, many people have turned to traditional medicines that are considered more safe and economical, because they use natural ingredients. Natural ingredients contain several active compounds which give pharmacological effects. In general, those active compounds are secondary metabolites.