Anti-Inflammatory Activity of Centella Asiatica Mediated Sil | 89458

Journal of Research in Medical and Dental Science
eISSN No. 2347-2367 pISSN No. 2347-2545

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Anti-Inflammatory Activity of Centella Asiatica Mediated Silver Nanoparticles

Author(s): S Ganesh, Abirami Arthanari* and S Rajeshkumar


Introduction: Inflammation is the body's main reaction to an illness or injury, and it is vital to our immunity. Because of the increasing prevalence of pain and pain-related disorders, as well as other health treatment complexities, it is important to be mindful of the anti-inflammatory medications available on the market. Furthermore, nonsteroidal anti-inflammatory medications have been related to side effects including stomach pain, heartburn, and ulcers. So, this study deals with the anti-inflammatory activity of Centella mediated silver nanoparticles Materials and methods: Collection of Centella asiatica extract then 1 g of Centella asiatica, leaf powder was dissolved in distilled water and boiled for 5–10 min at 60–70C. The solutions were then filtered using Whatman No. 1 filter paper. The filtered extract was collected, synthesis of silver nanoparticles using an herbal formulation, and to finalize the anti-inflammatory activity of silver nanoparticles. Result: Anti-inflammatory activity of silver nanoparticles show an incremental pattern with increase in concentration, where percentage of inhibition is high at 50μl. Its activity increases with increase in dosage. Conclusion: This study thus provides a strong base for understanding the anti-inflammatory activity of silver nanoparticles.

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