Biomechanical and Histomorphometric Analysis of Max Phase (Ti2AlC) Alloy as an Implant
Background: The type of implant material for bone in growth with appropriate biomechanical properties has long been sought as the ideal bone-implant interface. This study aimed to assess the influence of Max phase alloy (Ti2AlC) implant on the new bone in growth and biomechanical (push out bond strength test) and this was in comparison with Ti6Al7Nb and cpTi.
Materials and methods: A cylindrical implants were prepared from Maxphase Ti2AlC, Ti6Al7Nb and cpTi with these dimensions (8 3) mm height and diameter respectively. In this study, White, male New Zealand rabbits, weighing (2-2.5 kg), aged (10-12 months) were used for implantation of implant cylinder in femur. Then biomechanical (push out bond strength test) and Histomorphometric analysis was performed after 2 and 6 weeks of post-surgical implantation. Statistical analysis was performed for data using SPSS version 24.
Results: In this research, Ti2AlC implants achieved the highest push out bond strength. and the recorded mean value for Ti2AlC (10.425+1.155) Mpa as compared with the Ti6Al7NB (7.7630+0.800) Mpa and cpTi implants (3.1440+0.779) Mpa after 2 weeks implantation in rabbit. Similarly, differences were observed after 6week implantation. For the histomorphometric analysis, TI2AlC implant recorded a statistically highly significant differences is in the mean values of bone and bone implant contact as compared with TI6Al7NB and cpTi.
Conclusions: with in limitation of the present study it can be concluded that, the bone implant interface strength of Max phase alloy Ti2AlC implant was higher than that of Ti6Al7Nb and cpTi after 2 and 6 weeks implantation in femur of rabbit. And this was coinciding with the higher amount of bone and bone implant contact associated with the same material.
Keywords: Bone healing, CPT, Ti6Al7Nb, Ti2AlC, Histomorphometric, Implant