Green Preparation of Gold Nano Particles Procured from Neem and Ginger Plant Extract to Evaluate the Antimicrobial Activity Against Oral Aerobic Pathogens
Author(s): Harsh Kasabwala*, Dhanraj Ganapathy and Rajeshkumar Shanmugam
Abstract
Gold has been used therapeutically in Chinese medicine since 2500 BC. Swarna Bhasma, or red colloidal gold, is still used in Indian Ayurvedic medicine for rejuvenation and revitalization in old age. Green metal nanoparticle synthesis is an important technique for developing more environmentally friendly nanoparticle production methods. The biomedically valid gold nanoparticle was synthesised in this study using Neem and Ginger plant extract. The transition of the extract from brown to pinkish red confirmed the synthesis of gold nanoparticles. Scanning Electron Microscope revealed triangle, rectangle, and square shaped gold nanoparticles with an average size of 60 nm (SEM). Energy dispersive analysis (EDS) was used to investigate the nature of elemental gold. Finally, the antibacterial activity of gold nanoparticles was tested; it was discovered that E faecalis had the highest level of inhibition, while S mutans, S Aureus and Candida Albicans and had a medium range of inhibition.