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Incidence of Subclinical Hypothyroidism in GDM With increased risk of Preterm Delivery | Abstract

Journal of Research in Medical and Dental Science
eISSN No. 2347-2367 pISSN No. 2347-2545

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Incidence of Subclinical Hypothyroidism in GDM With increased risk of Preterm Delivery

Author(s): V Sathya, Giridharan Bupesh, S Vasanth

Abstract

Metabolic and many endocrine changes during pregnancy are mainly due to the minor alterations in physiology of mother and fetus. The two common endocrinopathies during pregnancy are gestational diabetes mellitus and thyroid disorders. However, there is no suf????e?t evidence to prove the association between subclinical hypothyroidism, Gestational Diabetes Mellitus (GDM) and perinatal outcome. Hence, the present clinical investigation is to determine the combined morbidity of GDM and subclinical hypothyroidism and its association with adverse maternal and fetal outcomes. The rate of preterm delivery is elevated in GDM cases with SCH and 21% of SCH pregnant women had preterm delivery compared to 5.6% in euthyroid cases and was statistically s?g???????t (p=0.20). The studies also indicate an increased risk of subclinical hypothyroidism in women with GDM and maternal thyroid hormone status was related to the degree of metabolic imbalance. The screening for GDM in women during early pregnancy tends to reduce morbidity in foetus and mother through dietary or drug management. Furthermore, the study emphasizes on the importance of evaluation of thyroid function in women with GDM owing to the increase in high perinatal and neonatal morbidity

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