Journal of Research in Medical and Dental Science
eISSN No. 2347-2367 pISSN No. 2347-2545

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Pyoderma Gangrenosum with Extra-Cutaneous Manifestation and Elevated beta-2 Microglobulin in a Nigerian Child

Author(s): Lawan Musa Tahir*, Lokman Cam, Ramatu Muhammed Nafiu, Mesut Guler, Goksel Bahadir, Mehmet Sina Yilmaz and Senol Dane

Abstract

Pyoderma gangrenosum (PG) is an uncommon ulcerative cutaneous disease with unknown etiology. It is rare in children. It presents as a painful papular or papulo-pustular lesions which rapidly evolves into ulcers. Rarely, PG may present with extracutaneous manifestations. More than 50% of patients have underlying systemic diseases. Diagnosis is often delayed especially due to the absence of pathognomonic features. There are few reports of PG from Nigeria of which only one was child. We present a 10-year-old Nigerian boy who had PG with extra-cutaneous manifestation and elevated beta-2 microglobulin levels. Therefore, the elevated beta-2 microglobulin levels could be used as measures of diagnosis and improvement criteria of PG.

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