Stem Cell Based Bone and Periodontal Regeneration
The prime intention of periodontal regeneration is restoration of diseased and damaged alveolar bone proper, the cementum and PDL fibres into the root surface. Recent regenerative strategies, periodontal researches and stem cell regenerations show encouraging approaches towards the same. So far mesenchyme stem cells have shown potential for periodontal regeneration in animal studies. Most investigated among several MSC’s is Bone Marrow MSC’s (BMMSC), Periodontal Ligament Stem Cells (PDLSC’s) and Dental Pulp Stem Cells (DPSC’s).
A few studies have also been conducted on humans using BMMSC’s, PDLSC’s, DPSC’s and have been proven effective and safe. However to bring MSC based periodontal regeneration to regular clinical use, more studies need to be conducted.