Journal of Research in Medical and Dental Science
eISSN No. 2347-2367 pISSN No. 2347-2545

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The Formation of Parts of the Human Immune System under the Influence of Factors of Industrial Ecology (Example of the Military Type of Technogenesis)

Author(s): Ekaterina V Vasilieva*, Irina D. Sitdikova, Marina K. Ivanova, Elena Iu Startseva and Liudmila I Gerasimova

Abstract

Purpose of study: We conducted a study of the immune status of servicemen employed in chemical weapon storage and disposal enterprises. The paper presents the results of the analysis of the cellular and humoral immunity indicators taking into account the age of the servicemen and the distribution of the contingent. The paper also presents the results of the analysis of the NBTtest, which indicates the depletion of the immune status. The comparative analysis of the NBT-test showed higher than normal indicators in all age categories. The spontaneous NBT indicators show low levels in the age group of 18-29 years-2.2% of the subjects, the induced NBT indicators are below the norm in the age group of 18-29 years-2.2%, 30-39 years-4.5%. The servicemen have a pronounced change in the immunity indicators.

Methodology: Work at military enterprises is characterized by the impact of a number of chemical factors, in particular heavy metals, carbon monoxide, benzapyrene, on military personnel.

Result: Evaluation of the qualitative and quantitative characteristics of immunological indicators allows us to study the effect of individual indicators on the formation of the immune status in general. This position should be taken into account upon developing a set of preventive measures. Determination of the amount of immunoglobulins was carried out by the method of radial immunodiffusion. The parameters of cellular and humoral immunity were analyzed with the help of the nitro blue tetrazolium test (NBT-test). In the course of the study, the retired servicemen had a significantly increased leukocyte count (80.5% of the subjects), normal neutrophil count (85.4% of the subjects), T-lymphocytes (92.2% of the subj 7.6% of the subjects).

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