The Impact of Fixed Orthodontic Appliance on Oxidative Stress and Gingival Health Condition
Author(s): Reema FH Alshikhly*, Baydaa H Awn
Aim: The aim of this study was to find out the effect of orthodontic treatment on the oxidative stress of patients with fixed
orthodontic appliance in relation to the gingival health condition.
Material and Method: The subject population consisted of 31 participants who were in need of orthodontic treatment with
fixed orthodontic appliances. Saliva samples were obtained from all individuals before treatment, at 1st month of treatment
and at 3rd months of treatment. Clinical oral hygiene and Gingival (GI) parameters were measured. Samples were
investigated to detect Protein Carbonyl (PC), Total Antioxidant Capacity (TAC) levels using ELISA method and Uric Acid (UA)
level using spectrophotometer.
Results: All biochemical parameters levels detected in saliva at the 1st and 3rd months of orthodontic treatment is
statistically significant according to baseline (P<0.05), a significant positive correlation found between GI and PC at the 1st
Conclusion: Employing fixed orthodontic appliances has an impact on the oral environment. Fixed orthodontic treatments
result in Shifting in the oxidant-antioxidant balance with mild gingival inflammation.