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Outcomes of Laparoscopic Appendectomy in Eastern Region of Nepal

Journal of Research in Medical and Dental Science
eISSN No. 2347-2367 pISSN No. 2347-2545

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Research - (2022) Volume 10, Issue 3

Outcomes of Laparoscopic Appendectomy in Eastern Region of Nepal

Ravi Bastakoti1, Adarsh Jha2*, Rabin Raj Singh1, Trinetra Kumar Karna1, Kshitij Giri1, Sunil Regmi1 and Atul Dwivedi3

*Correspondence: Adarsh Jha, Vedanta Hospital, India, Email:

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Abstract

Introduction: Acute Appendicitis is the most common intraabdominal condition which requires emergency surgical treatment. Possibility of appendicitis should be ruled out in any patient presenting acute abdomen symptoms, and a sure preoperative diagnosis is still a challenging task. There are two ways to perform appendectomy. 1. Laparoscopic Appendectomy and 2. Open Appendectomy. Recently laparoscopic appendectomy has been gaining popularity in place of open appendectomy procedure. Appendectomy is a frequent surgical procedure. All surgical procedure has their own long term and short term potential complications. The main short term complications of appendectomy such as infections and intra- abdominal abscesses. Additionally, it's also important to assess the risk of long term complications for abdominal procedures such as ileum and incisional hernia. Finally, mortality is also a complication of surgery. Appendix is a part of digestive tract, but exact function of appendix is yet to be known. Appendix may be associated with immunological function in intestine. Material and method: Total number of cases undergone LA are 62. Methods: we completed a retrospective chart review of all patients undergoing LA for a clinical presentation of acute appendicitis from 2018 to 2020. Exclusion criteria included incidental appendectomy, appendectomy of less than 16 age group. All procedure is done in our hospital. Hospital charts were reviewed and all data collected and entered in to standardized data collection forms. We randomly choose 62 patients (30 female patients, 32 male patients) Results: Length of stay in hospital 25 patients=2 days 40% 20 patients=3 days 32% 12 patients=4 days 19% 3 patients-5 day 4.8% 1 patient-6 days 1.6% 1 patient-8 days 1.6% Post-operative Complications were identified in 14 patients Wound infection: 9 cases (out of 14 cases, 9 patients with post-operative wound infection). Out of these 9 patients, 2 needed secondary suturing. These wound infections were managed by opening and packing the wound. And no intraabdominal abscess was found in any patient. Peri-operative antibiotics were given to all patients. No patient was readmitted. No mortality found so far. 3 patients developed nausea, vomiting and loose stool. Benefits: Peritoneal lavage could be done for pus in other site than RIF in 16 cases. Other pathology found 2 patients had twisted ovarian cyst. Single patient had chocolate cyst for which all 3 had undergone appendectomy and cystectomy. At the end of procedure, each patient also had extensive irrigation of the operative site. Conclusion: Laparoscopic Appendectomy is a safe technique and clinically beneficial for the patients. It provides various advantages over open appendectomy such as short hospital stay, reduced amount and duration of post-operative analgesia, early food tolerance, early return to normal activities and least post-operative complications. Contrarily, several complications may occur in this procedure too. Hence, we should assess the condition of the patient to consider laparoscopic Appendectomy as procedure of choice for most of the case of appendicitis.

Keywords

Appendectomy, Acute appendicitis, Laparoscopic appendectomy, Open appendectomy

Introduction

Acute appendicitis is the most common non obstetric surgical complication that takes place during pregnancy, and it's occurrence rate ranges from 1.8 to 41 per 10,000 pregnancies [1-6]. Clinical diagnosis of AA is often involves a combination of clinical, laboratory and radiological findings. The diagnostic methods could be purifying with the involvement of clinical scoring system that involve physical examination finding and inflammatory markers. Many user-friendly scoring systems have been used in the form of organized algorithm for predicting the risk of AA, but none has been accepted worldwide [7-9]. Moreover, the role of ultrasound (USG), computed Tomography ( CT),or Magnetic Resonance imaging (MRI) is still controversial [10,11].

Appendectomy is the most common emergency surgical procedure [12,13]. Appendectomy is a simple and well standardized surgical procedure.

It can be of two types 1. Open 2. Laparoscopic.

The laparoscopic way seemingly superior to open approach in some aspects like pain, wound infection rate, and postoperative ileum [14,15].

Despite numerous studies, it is still not clear whether open appendectomy ( OA) or Laparoscopic Appendectomy is the most effective surgical procedure for acute appendicitis [16-23].

It's very challenging to diagnose acute appendicitis during pregnancy, because several nonspecific abdominal symptoms, physiologic leukocytosis

And anatomical changes associated with appendix during pregnancy [24].

Material and Methods

We completed a retrospective chart review of all patients undergoing LA for a clinical presentation of acute appendicitis from 2018 to 2020.

Exclusion criteria included incidental appendectomy, appendectomy of under 16 age group.All procedure are done in our hospital. Hospital charts were reviewed and all data collected and entered in to standardised data collection forms.

Results

Length of stay in hospital

25 patients=2 days

20 patients=3 days

12 patients=4 days

3 patients-5 day

1 patient-6 days

1 patient-8 days

Post-operative Complications were identified in 14 patients

Wound infection: 9 cases

Out of these 9 patients, 2 needed secondary suturing

These wound infections were managed by opening and packing the wound. And no intraabdominal abscess was found in any patient. Peri operative antibiotics were given to all patients.

No patient was readmitted. No mortality found in our study.

3 patients developed nausea, vomiting and loose stool.

Benefits

Peritoneal lavage could be done for pus in other site than RIF in 16 cases.

Other pathology found

2 had twisted ovarian cyst.

Single patient had chocolate cyst for which all 3 had undergone appendectomy and cystectomy.

At the end of procedure, each patient also had extensive irrigation of the operative site.

Moderate amount of post-operative analgesia required in all cases. No mortality reported so far.

Discussion

The success of laparoscopic surgery in gall bladder disease and many other fields has led to reevaluation of many open surgical procedures. Acute appendicitis (AA) is one of the most common conditions that requires emergency surgery. Laparoscopic surgery is a major surgical advancement since last two decades.

Several studies proved the safety, faster return to normal activities, fewer wound complications, and longer operating time in case of Laparoscopic Appendectomy [20,25].

Our study findings also matched with other studies in which laparoscopic appendectomy was performed on several patients. These studies also concluded that laparoscopy should be used as routine procedure for all young females presenting with right iliac fossa pain [26]. Additionally, laparoscopic appendectomy is associated with diminished morbidity in elderly patients [27]. Moreover, LA is safe for advance appendicitis in children [28]. On the basis of level of satisfaction, patients' preference during counseling, study suggested that LA may be adopted safely for cases of suspected appendicitis [29].

The Cochrane systematic review of Randomized controlled trials comparing LA and OA is regularly updated including 39 clinical trials [9]. This metaanalysis suggested that wound infections are about one- half as likely after LA. Additionally, intraabdominal abscesses occur almost 3 times more often after LA. The exact cause for increased occurrence of abscess formation after LA is still unknown [30], fortunately, we don't find any in our study. Another aspect is safety in such common procedures like appendectomy, where the number of procedures performed by each surgeon may be associated with number of complications like length of stay and cost [31,32].

On the other hand, if performed safely with Minimally invasive method, we can get higher success in clinical settings and also hospital stay may be less than one in 90% cases [33,34].

Appendicitis with pregnancy associated with poor pregnancy outcomes, including preterm delivery, fetal loss, and perinatal morbidity and mortality [11]. 20 % women suffered from fetal loss in case of complicated appendicitis, while only 1.5% of women suffered from the same in uncomplicated appendicitis [35-37].

The Preterm delivery takes place more frequently in perforated appendicitis, and preterm delivery rate has been reported to be between 7.5 and 30.0% [38-40]. In our study, no such cases found.

There are many limitations existing in our study. First one is the small sample size; second limitation is that our study is not able to clarify the guidelines for complications of LA during pregnancy. Finally, this study doesn't reveal factors, which can minimize the complications of LA. Last but not the least, this study doesn't talk about cost effectiveness of LA, might be LA is expensive for a large number of people in lower socioeconomic areas.

Conclusion

Laparoscopic Appendectomy is a safe technique and clinically beneficial for the patients. It provides various advantages over open appendectomy such as short hospital stay, reduced amount and duration of post-operative analgesia, early food tolerance, early return to normal activities and least post-operative complications.

Contrarily, several complications may occur in this procedure too. Hence, we should assess the condition of the patient to consider laparoscopic Appendectomy as procedure of choice for most of the cases of appendicitis.

Abbreviations

LA: Laparoscopic Appendectomy.

RIF: Right Iliac Fossa.

AA: Acute Appendicitis.

OA: Open Appendectomy.

USG: ultrasound/Sonography.

CT: Computed Tomography.

MRI: (Magnetic Resonance imaging.

References

  1. Zingone F, Sultan AA, Humes DJ, et al. Risk of acute appendicitis in and around pregnancy: A population-based cohort study from England. Ann Surg 2015; 261:332-337.
  2. Indexed at, Google Scholar, Cross Ref

  3. Guttman R, Goldman RD, Koren G. Appendicitis during pregnancy. Can Fam Phys 2004; 50:355-7.
  4. Indexed at, Google Scholar

  5. Kristein B, Perry ZH, Avinoach L. Safety of laparoscopic appendectomy during pregnancy. World Journal Surg 2009; 33:475-480.
  6. Indexed at, Google Scholar, Cross Ref

  7. Wilasrusmee C, Sukrat B, McEvoy M, et al. Sytematic review and metaanalysis of safety of laparoscopic versus open appendectomy for suspected appendicitis in pregnancy.Br J Surg 2012; 99:1470-1478.
  8. Google Scholar

  9. Walker HG, Al Samaraee A, Mills SJ, et al. Laparoscopic appendicectomy in pregnancy: A systematic review of published evidence. Int J Surg 2014; 12:1235-41.
  10. Indexed at, Google Scholar, Cross Ref

  11. Tracey M, Fletcher HS, Hollenbeck JI, et al. Appendicitis in pregnancy/discussion. Am Surg 2000; 66:555.
  12. Google Scholar

  13. Andersson M, Andersson RE. The appendicitis inflammatory response score: A tool for the diagnosis of acute appendicitis that outperforms the Alvarado score. World J Surg 2008; 32:1843-1849.
  14. Indexed at, Google Scholar, Cross Ref

  15. Alvarado A. A practical score for the early diagnosis of acute appendicitis. Ann Emerg Med 1986; 15:557-564.
  16. Indexed at, Google Scholar, Cross Ref

  17. Gregory S, Kuntz K, Sainfort F, et al. Cost effectiveness of integrating a clinical decision rule and staged protocol for diagnosis of appendicitis. Value in Health 2016; 19:28-35.
  18. Indexed at, Google Scholar, Cross Ref

  19. Sammalkorpi HE, Mentula P, Leppäniemi A. A new adult appendicitis score improves diagnostic accuracy of acute appendicitis-a prospective study. BMC Gastroenterol 2014; 14:114.
  20. Indexed at, Google Scholar, Cross Ref

  21. Sippola S, Virtanen J, Tammilehto V, et al. The accuracy of low-dose computed tomography protocol in patients with suspected acute appendicitis: The OPTICAP study. Ann Surg 2018; 1.
  22. Indexed at, Google Scholar, Cross Ref

  23. https://www.scielo.br/j/abcd/a/WC53wJGwDxVG4FpBw9vMHyG/?lang=pt
  24. Slotboom T, Hamminga JT, Hofker HS, et al. Intraoperative motive for performing a laparoscopic appendectomy on a postoperative histological proven normal apêndix. Scand J Surg 2014; 15:232-236.
  25. Indexed at, Google Scholar, Cross Ref

  26. Vettoretto N, Gobbi S, Corradi A, et al. Consensus conference on laparoscopic appendectomy: Development of guidelines. Colorectal Dis 2011; 13:748-754.
  27. Indexed at, Google Scholar, Cross Ref

  28. http://www.sages.org
  29. Golub R, Siddiqui F, Pohl D, et al. Laparoscopic versus open appendectomy: A meta-analysis. J Am Coll Surg 19988; 186:545-53.
  30. Indexed at, Google Scholar, Cross Ref

  31. Slim K, Pezet D, Chipponi J. Laparoscopic or open appendectomy? Critical review of randomized Zeffiro, controlled trials. Dis Colon Rectum 1998; 41:398-403.
  32. Indexed at, Google Scholar, Cross Ref

  33. Chung RS, Rowland DY, Li P, et al. A meta-analysis of randomized controlled trials of laparoscopic versus conventional appendectomy. Am J Surg 1999; 177:250-256.
  34. Indexed at, Google Scholar, Cross Ref

  35. Fingerhut A, Millat B, Borrie F. Laparoscopic versus open appendectomy: Time to decide. World J Surg 1999; 23:835-45.
  36. Indexed at, Google Scholar, Cross Ref

  37. Dai L, Shuai J. Laparoscopic versus open appendectomy in adults and children: A meta-analysis of randomized controlled trials. United Eur Gastroenterol J 2017; 5:542-53.
  38. Indexed at, Google Scholar, Cross Ref

  39. Meynaud-Kraemer L, Colin C Vergnon P, et al. Wound infection in open versus laparoscopic appendectomy. A meta-analysis. Int J Technol Assess Health Care 1999;15:380-91.
  40. Indexed at, Google Scholar

  41. Temple LK, Litwin DE, McLeod RS. A meta-analysis of laparoscopic versus open appendectomy in patients suspected of having acute appendicitis. Can J Surg 1999; 42:377-83.
  42. Indexed at, Google Scholar

  43. Sauerland S, Lefering R, Neugebauer EAM. Laparoscopic versus open surgery for suspected appendicitis (Conchrane review). In: The Conchrane Library 2004.
  44. Indexed at, Google Scholar, Cross Ref

  45. Seung HL, JY Lee, JG Lee et a. Laparoscopic appendectomy versus open appendectomy for suspected appendicitis during pregnancy: A systematic review and updated meta-analysis. BMC Surg 2019; 19:41.
  46. Indexed at, Google Scholar, Cross Ref

  47. Sauerland S, Lefering R, Holthausen U, et al. Laparoscopic vs. conventional appendectomy-a meta-analysis of randomized controlled trials. Langenbeck Arch Surg 1998; 383:289-295.
  48. Indexed at, Google Scholar, Cross Ref

  49. Garbarino S, Shimi SM. Routine diagnostic laparoscopy reduces the rate of unnecessary appendicectomies in young women. Surg Endosc 2009; 23:527-533.
  50. Indexed at, Google Scholar, Cross Ref

  51. Kirshtein B, Perry ZH, Mizrahi S, et al. Value of laparoscopic appendectomy in the elderly patient. World J Surg 2009; 33:918-922.
  52. Indexed at, Google Scholar, Cross Ref

  53. Nwokoma NJ, Swindells MG, Pahl K, etal. Pediatric advanced appendicitis: Open versus laparoscopic approach. Surg Laparosc Endosc percuta Tech 2009; 19:110-113.
  54. Indexed at, Google Scholar, Cross Ref

  55. Shaikh AR, Sangrasi AK, Shaikh GA. Clinical outcomes of laparoscopic versus open appendectomy. J Society Laparoendoscopic Surg 2009; 13:574.
  56. Indexed at, Google Scholar, Cross Ref

  57. Rohit Gupta, Cliff S, Fahad Bamehriz, et al. Infectious complications following laparoscopic appendectomy. Can J Surg 2006; 49:397-400.
  58. Indexed at, Google Scholar

  59. Sauerland S, Jaschinski T, Neugebauer EA. Laparoscopic versus open surgery for suspected appendicitis. Cochrane Database of Systematic Rev 2010.
  60. Indexed at, Google Scholar, Cross Ref

  61. Cawing SO, Mohanty SK, Simpson LK, et al. Is laparoscopic appendectomy safe when performed in a low volume setting? Int J Biomed Sci 2014; 10:31-35.
  62. Indexed at, Google Scholar

  63. Cross W, Chadru KG. Same day surgery for laparoscopic appendectomy in appendicitis: is this safe? Am Surg 2014; 80:25-26.
  64. Indexed at, Google Scholar

  65. Frazee RC, Abernathy SW, Davis M, et al. Outpatient laparoscopic appendectomy should be the standard of care for uncomplicated appendicitis. J Trauma Acute Care Surg 2014; 76:79-82.
  66. Indexed at, Google Scholar, Cross Ref

  67. Palanivelu C, Rangarajan M, Senthilkumaran S et al. Safety and efficacy of laparoscopic surgery in pregnancy: experience of a single institution. J Laparoendosc Adv Surg Tech A 2007; 17:186-90.
  68. Indexed at, Google Scholar, Cross Ref

  69. Park SH, Park MI, Choi JS, et al. Laparoscopic appendectomy performed during pregnancy by gynaecological laparoscopists. Eur J Obstet Gynecol Reprod Biol 2010; 148:44-48.
  70. Indexed at, Google Scholar, Cross Ref

  71. Andersen B, Nielsen TF. Appendicitis in pregnancy: Diagnosis, management and complications. Acta Obstet Gynecol Scand 1999; 78:758-762.
  72. Indexed at, Google Scholar

  73. Yoo KC, Park JH, Pak KH, et al. Could laparoscopic appendectomy in pregnant women affect obstetric outcomes ? A multicenter study. Int J Color Dis 2016; 31:1475-81.
  74. Indexed at, Google Scholar, Cross Ref

  75. Karaman E, Aras A, Çim N, et al. Maternal and fetal outcomes after laparoscopic vs.open appendectomy in pregnant women: Data from two tertiary referral centers. Ginekol Pol 2016; 87:98-103.
  76. Indexed at, Google Scholar, Cross Ref

  77. Cheng HT, Wang YC, Lo HC, et al. Laparoscopic appendectomy versus open appendectomy in pregnancy: A population based analysis of maternal outcome. Surg Endosc 2015; 29:1394-1399.
  78. Indexed at, Google Scholar, Cross Ref

Author Info

Ravi Bastakoti1, Adarsh Jha2*, Rabin Raj Singh1, Trinetra Kumar Karna1, Kshitij Giri1, Sunil Regmi1 and Atul Dwivedi3

1Koshi Hospital, Biratnagar, Nepal, India
2Vedanta Hospital, Itahari, Nepal, India
3Shivaanan Polyclinic, Bareilly, Uttar Pradesh, India
 

Received: 07-Feb-2022, Manuscript No. JRMDS-22-53712; , Pre QC No. JRMDS-22-53712 (PQ); Editor assigned: 09-Feb-2022, Pre QC No. JRMDS-22-53712 (PQ); Reviewed: 23-Feb-2022, QC No. JRMDS-22-53712; Revised: 25-Mar-2022, Manuscript No. JRMDS-22-53712 (R); Published: 02-Mar-2022

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