D Ezhilarasan

Department of Pharmacology, Saveetha Dental College and Hospitals, Saveetha Institutes of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, India


  • Research   
    In-vitro Anticancer Activity of Cardiospermum Halicacabum against Human A549 Lung Cancer Cell
    Author(s): Harita Ravikumar, S Raghunandhakumar*, D Ezhilarasan and Lakshmi T

    Introduction: Lung cancer is the major type of cancer that is developing all over the world. Approximately 1.8million new people were affected by lung cancer in 2012 among which 1.6million people were fatal. Cardiospermum halicacabum is also known as balloon vine, climber plant. It belongs to order sapindaceae and it has a high medicinal value. AIM: To assess the anticancer activity of Cardiospermum halicacabum against human A549 lung cancer cell line. Materials and method: The anticancer effect of cardiospermum halicacabum on A549 was measured by MTT assay and the cell morphological evaluation done by inverted phase contrast microscopy. Results and Discussion: From the MTT assay plant extract of Cardiospermum halicacabum showed approximately 50% cell inhibition at 30µl/ mg concentration after 24hrs of treatment. Further it was confirmed with morphological evaluation using phase.. Read More»

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