Iffat Nasim
Department Conservative Dentistry and Endodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University Tamilnadu, Chennai, IndiaPublications
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Research
Evaluation of Antimicrobial Activity and Cytotoxicity of Biogenic Gold Nanoparticles
Author(s): K Ajith Kamath, Iffat Nasim* and S Rajesh
Gold nanoparticles are some among the most researched nanomaterials in the field of nanotechnology. They can be easily synthesised and show excellent chemical as well as thermal stability. Biosynthesized nanoparticles offer excellent biocompatibility compared to nanoparticles synthesized by any other physicochemical methods. The main objective of this study was to analyze the antimicrobial activity of the gold nanoparticles synthesised with aspartic acid and to evaluate its cytotoxicity at the embryonic level. The antimicrobial activity of the AuNPs was assessed by the well diffusion method using different clinical pathogenic bacteria namely, E faecalis, S.mutans, Pseudomonas, and S. aureus. Zebrafish were selected for this study to analyze the cytotoxicity of the AuNPs. The zone of inhibition was seen to be the largest in E. faecalis(20mm) and smallest in S.aureus (.. Read More»