Manikantan Sekar

India

Publications

  • Research   
    Effects of Individualized Dialysate Sodium in Hemodialysis
    Author(s): Kawin Gunasekaran, E Ramprasad Elumalai, M Jayakumar and Manikantan Sekar*

    Sodium is the major extracellular cation in the body and hence and is the major determinant of extracellular fluid (ECF) content and serum osmolarity. Volume overload contributed by increased sodium is a major problem in patients on hemodialysis (HD). Sodium entry occurs in hemodialysis patients from dietary intake, dialysis fluid or from saline infusions given during the hemodialysis session. Currently, all patients undergoing maintenance hemodialysis in our centre and hospitals world-wide are dialysed with dialysate sodium of 138 meq/L and this dialysate sodium level used as a standard value in all patients irrespective of their blood sodium values. Patients undergoing dialysis have an individualized sodium and osmolarity value which are known as sodium and osmolar set point . respectively, and are unique for each patient and is highly conserved. A higher dialysate sodium concentrat.. Read More»

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