Mohammad Arjomandzadegan
Infectious Diseases Research Center, Arak University of Medical Sciences, Arak, IranPublications
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Original Article
Growth Control of Acinetobacter baumannii in Infected Wound by Oregano Essential Oil in Rats
Author(s): Mahmood Amini, Ghasem Habibi, Siamak Rakei, Saeid Heidari, Hanieh Taheri, Rozita Baba Esfahani, Maryam Sadrnia, Marjan Salehi and Mohammad Arjomandzadegan*
Introduction: Acinetobacter baumannii known as a main agent in nosocomial infections and its drug resistance is a medical problem in hospitals. In the present study, growth control of Acinetobacter by Oregano essential oil was investigated in-vitro and in experimental wounds on rats. Materials and Methods: Oregano essential oil (OES) was prepared by a Clevenger apparatus in a hydrodistillation process. Susceptibility of clinical isolate of Acinetobacterto essential oil was evaluated by disk diffusion and microbroth dilution methods. Ketamine and xylazine were used for surgical anesthesia induction in rats. The backs of 30 rats were shaved and an experimental wound in one square inch was prepared between two scapulae. All the ulcers were infected with fresh culture of Acinetobacter. The rats were divided into three .. Read More»