Murtadha Saleh Hussien
Department of Pharmacognosy and Medicinal Plants, College of Pharmacy, University of Baghdad, Baghdad, IraqPublications
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Research Article
Polyphenolic Compounds from Lactuca serriola Aerial Parts Growing in Iraq Exhibit Anticancer Properties and Concurrent HPLC-DAD Profiling
Author(s): Murtadha Saleh Hussien and Ayad A Al-Hamashi*
The present study was carried out to investigate the phytochemical constituent of Iraqi Lactuca serriola aerial part and to evaluate the cytotoxic effect of plant. The aerial part of Lactuca serriola were collected, dried, pulverized, and extracted with methanol using Soxhlet. The extract was concentrated, and the resulting residue was successively partitioned with solvent have different polarity including hexane, chloroform, ethyl acetate, N-butanol. The result fractions were subjected to general phytochemical screening, thin layer chromatography and High Performance Liquid Chromatography (HPLC) analysis. The results indicated the presence of phytosterol in the hexane fractions and the phenolic substances in the other fractions. Quercetin, chlorogenic acid, caffeic acid, lactucin, rutin, and quercetrin are six active constituents that were identified from Iraqi Lactuca serriola's.. Read More»