Nada Tawfig Hashim

Faculty of Dentistry, University of Science and technology, Khartoum, Omdurman, Sudan


  • Research   
    Assessment of the Level of Interleukin-12 in Gingival Crevicular Fluid of a Group of Patients with Aggressive Periodontitis and a Group of Healthy Subjects
    Author(s): Nada Tawfig Hashim* and Marwa Mohamed Sidahmed

    Background: Aggressive periodontitis is a type of periodontal disease that is relatively prevalent among Sudanese population. The disease generally affects younger individuals and might lead to tooth loss if undetected early leading to costly and long periodontal treatment. Until today, no reliable detection tool is present so, diagnosis is confirmed only after periodontal tissue loss has already occurred. Cytokines play a major role in the initiation and also progression of this disease. Interleukin 12 has both pro-inflammatory and immune-regulatory effects and it has been implicated in the pathogenesis of other inflammatory diseases such as rheumatoid arthritis. However, it was not studied extensively in Sudanese population. Therefore, the aim of this study was to measure and compare the level of Interleukin 12 in the gingival crevicular fluid of patients with aggressive periodontit.. Read More»

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