Senthil Murugan P

Department of Oral & Maxillofacial Surgery, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Science, Saveetha University Tamilnadu, Chennai, Tamil Nadu, India


  • Research   
    Comparison of Efficacy of Articaine and Bupivacaine after Impacted Third Surgery: A Double-Blinded Randomized Controlled Trial
    Author(s): Rezin Ahmed*, MR Muthusekhar and Senthil Murugan P

    Objective: This randomized controlled clinical trial(RCT) aims to compare the effect of bupivacaine and Articaine at normal doses on pain intensity and the requirement for analgesics after lower third molar extraction. Materials and methods: The final study sample comprised 50 volunteers (26 males and 24 females; age range, 18-30 years) undergoing scheduled surgical extraction of the impacted lower third molar. A computer-generated random sequence was used to allocate participants to the articaine (4%) or bupivacaine (0.5%) group. Surgeons and patients were blinded by labeling the articaine and bupivacaine carpules with numbers (1 and 2, respectively). Postoperative pain intensity (primary outcome) was evaluated with a visual analog scale (VAS), while the requirement for and timing of rescue medication and the quality of intraoperative anesthesia were also measured (secondary outcomes.. Read More»

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