Sonal Setya

Department of Pharmacy Practice, SGT University, Gurugram (HR), India

Publications

  • Research   
    A Study on Structure and Function of Coronavirus Spike Proteins
    Author(s): Sonal Setya*, Arminder Kaur, Divya Prakash and Ramneet Kaur

    Coronavirus spike enzyme, like a cell-invading biological mechanism, due of their great diversity, they provide an evolutionary challenge. This review paper discovered the cryo-EM structures of the genus' avian respiratory syncytial coronavirus spike proteins. The trimeric n?lƒmmƒo› Bronchitis Virus (IBV) spike ectodomain is made up of 3 receptors binding S1 head as well as trimeric membranes lipid S2 stalks. IBV S1 spans the gap between these different spikes and forms an evolutionary spectrum, whereas IBV S2 is structurally akin to those from new genera, and two S1 domain, comprising the N terminals domains (S1-NTD) or the C-terminals domains deviate from simple tertiaries structure or quaternaries packing to the more complicated ones across various species, resulting in varied roles of the spike in receptors use or membranes synthesis. Based on the system and functionals simil.. Read More»

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