Srivalsa Bhaskaran
Department of Microbiology, Sree Balaji Medical College and Hospital, Bharath Institute of Higher Education and Research, IndiaPublications
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Research
Efficacy Ratio Based Comparison of Susceptible Minimum Inhibitory Concentration of Antibiotics in E. coli Isolates of Bacteremia-A Retrospective Study
Author(s): Priya Venkatachalam*, Chitralekha Saikumar and Srivalsa Bhaskaran
Introduction: It is necessary to compare the susceptible minimum inhibitory concentrations (MIC) of different antibiotics to choose the appropriate one. Direct comparison of MICs cannot be done since the breakpoints are different for each antibiotic. In this scenario Efficacy ratio(ER) of an antibiotic can be determined .This is the ratio between the susceptible breakpoint and the susceptible MIC of the specific antibiotic. The therapeutic efficacy is directly proportional to the ER value. ER is a significant factor in antimicrobial agent selection and a very useful tool in planning the empirical therapy. Aim: To calculate the Efficacy ratio of susceptible minimum inhibitory concentrations of antibiotics in E.coli isolates of bacteremia and select the appropriate antibiotic for treatment. Materials and methods: Retrospectively study the Vitek 2 derived susceptible minimum inhibitory c.. Read More»