Thukaa Z Abdul-JalilDepartment of Pharmacognosy and Medicinal Plants, College of Pharmacy, University of Baghdad, Baghdad, Iraq
Evaluation of the Anti-inflammatory of Leucaena leucocephala extracts in Experimental Rats.
Author(s): Azal Satar Al-Baaj*, Thukaa Z Abdul-Jalil and Ammar A Fadhil
A lot of previous studies are concerned with the evaluation of the anti-inflammatory activity of medicinal plants because it considered cheap and are believed to possess minimal side effects. Leucaena leucocephala didn’t evaluate globally for its anti-inflammatory effect yet though some of it’s already separated and identified secondary metabolites were studied and proved to exert many pharmacological activities besides their effect on lowering the pro-inflammatory cytokines like TNF-α and IL-6. So, there was an interest to evaluate the biological effect of Leucaena leucocephala as a novel anti-inflammatory agent was the first motivation to start an in vivo study using a rat population. The N-butanol and ethyl acetate extracts were chosen to undergo this study since they contain a lot of the polyphenolic compounds (flavono.. Read More»