A Revolutionary Journey of Platelet Concentrates in Dentistry: A Review
Author(s): Kushal P Bhuskute*, Anuja Ikhar, Pradnya Nikhade, Akshay Jaiswal and Kajol Relan
Abstract
Platelet concentrates seem to be blood derivatives made from the blood of patient, inside which activated platelets have been captured within the fibrin matrix scaffold and cytokines, release growth factors included in tissue regeneration processes like cell proliferation and differentiation, extracellular matrix synthesis, chemo taxis, and angiogenesis. Over the last twenty years, these procedures have been found to enhance healing in soft as well as hard tissues, leading to beneficial therapeutic applications in dental professions. Numerous preparations were produced from various leukocyte content, fibrin network structures, and growth factors, and consequently different physical and physiological properties and applications, related to different centrifugation speeds and times, introducing chemicals, as well as the choice of supernatants and precipitates. A biological reason behind the method of preparation on certain conditions and scientific evidence applications of various platelet concentrates, into several domains in dentistry shall be discussed.